Removal of heat source in pure water
Ultrapure water heat source analysis: The difference between pure heat-free water and sterile water.It is generally believed that pyrogen is a bacterial pyrogen that originates from the extracellular iliac crest of the Gram-negative bacterium, that is, a fragment of the corpse of the bacterium.
There are two types of heat: one is a low molecular mass heat-generating material, and the other is a high-molecular mass heat-generating material, which are collectively referred to as endotoxins.
The main ingredient is lipopolysaccharide (LPS), and its relative molecular mass varies from a few thousand to hundreds of thousands (some think that the relative molecular mass is generally 10,000 to 25,000), depending on the type of bacteria that produce it. In the aqueous solution form an association, the relative molecular mass can reach 500,000 to 1 million (or even several million). This type of material has heat resistance and chemical stability and is not easily destroyed.
In addition, it has recently been revealed that lipid A is also a pyrogenic substance and constitutes an endotoxin that harms the human body and has a relative molecular weight of approximately 2000.
Therefore, the selection of the relative molecular weight of the ultrafiltration membrane used to remove the pyrogen needs to be determined based on the actual conditions of the liquid.